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Spring 2006 talks

01/20/2006 Ping Ma, Statistics 
01/27/2006 Brendan Frey, Engineering (U. Toronto) 
02/03/2006 Charles Whitfield, Entomology 
02/17/2006 Jose Meseguer, Computer Science 
02/24/2006 Xinguang Zhu, Plant Science 
03/03/2006 Jing Jiang, Computer Science 
03/10/2006 Bioinformatics Summit Week 
03/17/2006 Carlos Santos, Bioinformatics (U. Mich.) 
03/24/2006 UIUC spring break 
03/31/2006 Mike Colvin, Natural Sciences (UC-Merced) 
04/07/2006 No meeting 
04/14/2006 Huixia (Judy) Wang, Statistics 
04/21/2006 Jay Mittenthal, Cell & Structural Biology 
04/28/2006 William Hersh, Medical Informatics (OHSU) 
05/05/2006 Michael Erdmann (Carnegie Mellon) 
Fall 2005 talks

08/26/2005 Sheng Zhong, Bioengineering 
09/02/2005 Richard LeDuc, NIDA Center for Neuroproteomics 
09/09/2005 Xifeng Yan, Computer Science 
09/16/2005 Xu Ling, Computer Science 
09/23/2005 Saurabh Sinha, Computer Science 
09/30/2005 Hui Fang, Computer Science 
10/07/2005 Bruce Schatz, Medical Information Sciences 
10/14/2005 Kathy Lu, Bioengineering 
10/21/2005 Peter Bajcsy, NCSA 
10/28/2005 Uriel Kitron, Veterinary Medicine 
11/04/2005 Denis Larkin, Animal Sciences 
11/11/2005 Matthew Hudson, Crop Sciences 
12/02/2005 Sandra Rodriguez-Zas, Animal Sciences 
Spring 2005 talks

Charles Whitfield (Entomology) 1/28/05 
Peter Bajcsy (Automated Learning Group) 2/4/05 
Wei Xie (Chemical & Biomolecular Engineering) 2/11/05 
Gustavo Caetano-Anolles (Crop Science) 2/18/05 
Bruce Schatz (GSLIS; IGB) 2/25/05 
Xinguang Zhu (Plant Science) 3/4/05 
Gary Olsen (Microbiology) 3/11/05 
Tao Tao (Computer Science) 3/18/05 
Sameer Varma (Biophysics and Computational Biology) 4/1/05 
Christine Elsik (Texas A&M Univ.) 4/8/05 
Xin He (Bioinformatics MS Option, Computer Science) 4/15/05 
Xinghua Lu (Medical Univ. of S. Carolina) 4/22/05 
Fall 2005 talks
Date Event Related link  
08/26/2005 Sheng Zhong, Bioengineering Sheng Zhong's home page 

Sheng Zhong, a new faculty member in Bioengineering at UIUC, will be our first presenter. The abstract for his talk appears below:

Slide set [PowerPoint]

Current Topics in Computational Biology

Sheng Zhong, Dept of Bioengineering, UIUC

Computational Biology has evolved rapidly from a tool into a discipline. Huge amounts of genomic data, including genome sequence, microarray data and a lot of others, have been produced with the hope to understand fundamental questions related to human health.

Computational developments that utilize genomic data to interrogate human health related problems are lacking behind the speed of data generation. Better algorithms and computational tools on machine learning, scientific computing, intelligence system, data management and information retrieval are in great demand. How these algorithms and tools should be developed to interrogate the important biological and biomedical questions is the art that is open to discuss in this lecture.

Two biological questions and their related genomic data are going to be discussed. 1) How do stem cells work? 2) What causes cancer? In detail, can we computationally identify gene clusters based on gene expression profiles that best represent the functional relationship among genes? What is the gene regulatory network that initiates stem cell differentiation, or cancer formation? How do we decipher the relevant DNA sequence code so as to understand the genetic bases of cancer?

Background Reading:

1. BBC News on stem cells: http://news.bbc.co.uk/2/hi/science/nature/4155016.stm Also related stem cell news on the right panel of the browser.
2. Forbes's survey of venture capital on stem cells http://www.forbes.com/newsletter/2004/11/01/cz_sg_1101soapbox.htm
3. Science: Joining Forces for Brain Tumor Research http://www.sciencemag.org/cgi/content/full/309/5731/32b

Scientific Reading:
1. Microarray study on stem cells. http://www.sciencemag.org/cgi/content/abstract/298/5593/597
2. Brain tumor microarray study http://www.nature.com/nature/journal/v415/n6870/full/415436a_fs.html