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NMPDR User Guide

Intro to NMPDR

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What is NMPDR? 
What genomes are in NMPDR? 
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What genomes are in NMPDR?

The core pathogens are Category B food and water-borne diarrheagenic bacteria, Campylobacter jejuni, Vibrio cholerae, Vibrio parahaemolyticus, Vibrio vulnnificus, and Listeria monocytogenes. Also included are the enterotoxin B producing Staphylococcus aureus, as well as the re-emerging, antibiotic resistant pathogens Streptococcus pneumoniae and Streptococcus pyogenes (Group A Strep).

Because NMPDR curators rely on the comparative analysis of genomes to annotate subsystems, all publicly released, essentially complete genomes are entered into NMPDR. In the version released April 17, 2007, this amounted to 447 bacteria, 30 archaea, and 29 eukarya.

The NMPDR contains two classes of genomes -- those pathogens we are being funded to annotate, which we call "core genomes," and "supporting genomes," which include all publicly available genomes for comparative analysis. The table below lists core pathogens, with strain designation and serotype when known, and closely related supporting genomes.

Campylobacter Listeria Staphylococcus Streptococcus Vibrio
coli RM2228 fischeri ES114
fetus subsp. fetus 82-40 splendidus 12B01
lari RM2100 sp. MED222
upsaliensis RM3195 sp. Ex25 O62
epidermidis RP62A
epidermidis ATCC12228
haemolyticus JCSC1435
innocua 6a Clip11262 saprophyticus ATCC 15305 agalactiae serotype V 2603V/R
welshimeri 6b SLCC5334 agalactiae A909
agalactiae NEM316